Janumet is a combination of metformin and which medication

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Janumet is a unique medication that combines the proven benefits of metformin with the outstanding effectiveness of another medication. This powerful combination provides a comprehensive approach to managing blood sugar levels and promoting overall health.

Benefits of Janumet

Benefits of Janumet

Janumet is a combination medication that contains two active ingredients: sitagliptin and metformin. Sitagliptin works by increasing the levels of incretin hormones in the body, which helps to control blood sugar levels by stimulating the release of insulin and reducing the production of glucose in the liver.

Metformin, on the other hand, decreases the amount of sugar produced by the liver and increases the body’s response to insulin. Together, these two medications help to lower blood sugar levels in patients with type 2 diabetes.

Some of the benefits of Janumet include:

  • Effective in managing blood sugar levels
  • May help with weight loss
  • Convenient combination medication
  • Can be taken once or twice daily


The combination medication Janumet offers several benefits to individuals with type 2 diabetes. This dual-action drug combines metformin and sitagliptin to help control blood sugar levels. By working together, these two medications help to improve insulin sensitivity and reduce the absorption of glucose in the intestines.

Improved Glycemic Control: Janumet helps to lower fasting blood sugar levels, reducing the risk of hyperglycemia and its associated complications.

Convenience: Taking a single pill that contains two different medications can make managing diabetes treatment easier for some patients.

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Additional Benefits

Better tolerability: Some individuals find that the side effects of metformin are reduced when it is taken as part of the Janumet combination medication.


It is important to take Janumet exactly as prescribed by your healthcare provider. Typically, Janumet is taken with meals to help reduce the risk of stomach upset. The dosage of Janumet may vary depending on your individual condition and response to treatment. It is crucial to follow the directions provided by your healthcare provider to ensure the medication is effective and safe.

Important: Do not change the dosage or stop taking Janumet without consulting your healthcare provider first. Be sure to inform your doctor of any other medications or supplements you are taking to avoid potential interactions.

How to Take

Janumet is usually taken by mouth with a full glass of water. Some individuals may be advised to split the dosage throughout the day to maintain stable blood sugar levels. If you have any questions about how to take Janumet, consult your healthcare provider for guidance.


Janumet is taken orally, usually with a meal to minimize gastrointestinal side effects. It is important to follow the prescribed dosage and frequency as directed by your healthcare provider. The tablets should be swallowed whole with a full glass of water and should not be crushed or chewed. If you miss a dose, take it as soon as you remember unless it is close to the time of your next dose. Do not double up on doses to make up for a missed one.

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Recommended Dosage: Individual dosage will vary depending on your medical condition and response to treatment. Typically, the starting dose is one tablet of Janumet twice daily. Your healthcare provider may adjust the dosage based on your blood sugar levels.
Duration of Use: Continue taking Janumet for as long as prescribed by your doctor, even if you start feeling better. Do not discontinue the medication without consulting your healthcare provider.

Side Effects

Common side effects:

  • Nausea
  • Diarrhea
  • Headache
  • Dizziness

Less common side effects:

  • Low blood sugar
  • Joint or muscle pain
  • Skin reactions

If you experience any severe side effects or allergic reactions, seek immediate medical attention.

Side Effects

Janumet may cause certain side effects in some individuals. It is important to be aware of these potential reactions and consult with your healthcare provider if you experience any of the following:

Common Side Effects: Nausea, diarrhea, stomach upset, headache
Less Common Side Effects: Dizziness, joint pain, respiratory infections
Serious Side Effects: Allergic reactions, pancreatitis, kidney problems

If you notice any severe side effects or allergic reactions such as swelling, difficulty breathing, or severe abdominal pain, seek medical attention immediately. It is important to report any side effects to your healthcare provider to ensure safe and effective medication management.

Possible Reactions

It is important to be aware of the possible reactions that may occur while taking Janumet. Some common side effects include nausea, diarrhea, and stomach upset. These side effects usually go away on their own as your body adjusts to the medication.

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If you experience more serious reactions such as severe stomach pain, vomiting, or signs of pancreatitis (e.g., severe abdominal pain, nausea, vomiting), you should seek immediate medical attention. Allergic reactions to Janumet are rare but can include rash, itching, swelling, severe dizziness, or trouble breathing. If you notice any of these symptoms, stop taking Janumet and contact your doctor right away.

Key Points

1. Monitor for common side effects like nausea and diarrhea.

2. Seek medical attention for severe stomach pain or signs of pancreatitis.


Before taking Janumet, it is important to inform your healthcare provider about any allergies you may have, especially to metformin or sitagliptin. Additionally, let your doctor know about your medical history, especially if you have kidney disease, liver disease, heart problems, or a history of pancreatitis.

While taking Janumet, it is important to monitor your blood sugar regularly as directed by your doctor. Keep all appointments for blood tests and follow your doctor’s instructions closely. Be cautious when consuming alcohol while on Janumet as it can increase the risk of lactic acidosis.

Pregnancy and Breastfeeding

If you are pregnant or planning to become pregnant, consult your doctor before using Janumet. It is essential to discuss the risks and benefits of taking this medication during pregnancy. Janumet may pass into breast milk, so talk to your doctor before breastfeeding while on this medication.

Drug Interactions Inform your healthcare provider about all the medications you are currently taking, including prescription drugs, over-the-counter medications, vitamins, and herbal supplements. Some drugs may interact with Janumet, affecting its effectiveness or increasing the risk of side effects.